Vasculearn Network
For healthcare professionals

Atherosclerotic Cardiovascular Disease (ASCVD)

Atherosclerotic Cardiovascular Disease (ASCVD)

Health Equity

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Medication costs, coverage restrictions, language barriers, transportation, and work or caregiving demands can limit treatment options. An unfilled prescription or missed follow-up may reflect those barriers rather than a patient’s willingness to participate in care. Treatment discussions should account for what patients can realistically access and sustain.

Support requires infrastructure

Prior authorizations, medication access, interpreters, follow-up testing, and cardiac rehab require time and coordination. Where available, shared workflows with pharmacy, nursing, and care coordination can reduce the burden on patients and clinicians. Clear ownership of next steps helps prevent delays and missed follow-up.

Look for patterns in missed care

When data and staff capacity allow, examine where screening, treatment intensification, or referrals fall short, and whether gaps differ by language, insurance coverage, sex, or race and ethnicity. The purpose is to identify barriers that your practice or health system can realistically address.

Resources & References

Guidelines

Full guidelines, practical tools, and supporting publications are listed separately below.

*For lipid management and risk estimation, use the 2026 dyslipidemia guideline rather than the older lipid recommendations in the 2019 prevention guideline.

Additional guidance & clinical tools

References

1. Blumenthal RS, Morris PB, Gaudino M, et al. J Am Coll Cardiol. 2026;87(19):2624-2757. doi:10.1016/j.jacc.2025.11.016

2. Virani SS, Newby LK, Arnold SV, et al. J Am Coll Cardiol. 2023;82(9):833-955. doi:10.1016/j.jacc.2023.04.003

3. Rao SV, O’Donoghue ML, Ruel M, et al. J Am Coll Cardiol. 2025;85(22):2135-2237. doi:10.1016/j.jacc.2024.11.009

4. Gulati M, Levy PD, Mukherjee D, et al. J Am Coll Cardiol. 2021;78(22):2218-2261. doi:10.1016/j.jacc.2021.07.052

5. Mach F, Koskinas KC, Roeters van Lennep JE, et al. Eur Heart J. 2025;46(42):4359-4378. doi:10.1093/eurheartj/ehaf190

6. Patel SB, Belalcazar LM, Afreen S, et al. Endocr Pract. 2025;31(10):1207-1238. doi:10.1016/j.eprac.2025.07.014

7. Wiggins BS, Barac A, Benziger CP, et al. J Am Coll Cardiol. 2026;87(19):2617-2623. doi:10.1016/j.jacc.2026.02.4872

8. Lee YJ, Lee SJ, Kim JW, et al. N Engl J Med. 2026;394(14):1365-1375. doi:10.1056/NEJMoa2600283

9. Kumbhani DJ, Gibson CM, Kinlay S, et al. J Am Coll Cardiol. 2026;88(11):1284-1313. doi:10.1016/j.jacc.2026.05.037

10. Jones DW, Ferdinand KC, Taler SJ, et al. J Am Coll Cardiol. 2025;86(18):1567-1678. doi:10.1016/j.jacc.2025.05.007

11. Arnett DK, Blumenthal RS, Albert MA, et al. J Am Coll Cardiol. 2019;74(10):e177-e232. doi:10.1016/j.jacc.2019.03.010

12. American Diabetes Association Professional Practice Committee for Diabetes. Diabetes Care. 2026;49(suppl 1):S216-S245. doi:10.2337/dc26-S010

13. Agarwala A, Patel J, Stephens J, et al. Circulation. 2023;148(15):1183-1193. doi:10.1161/CIR.0000000000001171

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